AWvi The 360 Protocol

The 360 Protocol is AWvi’s most complete therapeutic system, designed to act across the entire skin ecosystem: from the intestinal lumen to the stratum corneum. By combining targeted nutraceutical and dermocosmetic interventions, it addresses the biological roots of skin dysfunction, including chronic inflammation, microbial imbalance, impaired barrier integrity, and extracellular matrix decline.

Each solution within the protocol serves a distinct physiological function while sharing a common biomimetic formulation logic. Together, they work in synergy to support immune regulation, restore balance to both the gut and skin microbiomes, optimise hydration gradients, and promote tissue repair. Suitable for a wide range of patient profiles, including skin in a sensitised, inflamed or prematurely aged state, The 360 Protocol offers a structured, layered approach to skin regeneration, both as a stand-alone protocol and as a home-care system that enhances and prolongs the outcomes of clinical and aesthetic treatments.

Clinical rationale

• Acts from the inside out and the outside in, targeting key checkpoints of dysregulation across the gut–skin axis, epidermis and dermis
• The Skin Biotic delivers three DNA-characterised proprietary probiotic strains, selected for their efficacy in modulating systemic inflammatory pathways, supporting mucosal barrier integrity, and promoting the production of short-chain fatty acids (SCFAs)
• Includes a prebiotic substrate to support beneficial microbial diversity and metabolite production
• The Gentle Cleanser preserves barrier integrity while preparing the skin for active treatments; formulated with ectoin to buffer oxidative and osmotic stress, high molecular weight sodium hyaluronate for superficial hydration and biomimetic lipids to maintain epidermal cohesion
• The Power Serum offers deep and surface hydration via broad-spectrum sodium hyaluronate, with molecular weights acting across all skin layers to reduce TEWL, support cell signalling and ECM repair
• It contains ectoin and pharmaceutical-grade biomimetic lipids to reinforce the skin's stress response and barrier regeneration
• The Active Cream completes the topical sequence with barrier-strengthening, lipid-replenishing and soothing ingredients, supporting dermal recovery and long-term comfort
• The full protocol is pH-balanced, non-occlusive and suitable for sensitive, reactive and inflammatory-prone skin
• Clinical testing demonstrates synergistic benefits when used as a complete protocol, with enhanced outcomes in hydration, elasticity, barrier function and inflammation regulation

Recommended use

• Comprehensive physiological regulation for patients with multi-layered skin dysregulation: microbial, immune and barrier-related
• Indicated for skin in a chronically inflamed, dehydrated, sensitised or environmentally compromised state
• Suitable as a complete protocol for skin regeneration, or integrated selectively into existing treatment regimens
• An optimal home-care strategy pre- and post-procedure, to prepare the skin, increase treatment efficacy, and prolong clinical outcomes
• Especially valuable in protocols involving aesthetic, dermatological, or medical interventions requiring biological recovery support